If you're running LOGIC the default patch for the EXS24 sampler is a heavy sine wave.
Just tweak the release and you're good to go. Throw a mid range lead over it with the same notation data on that track so they sync up. Sometimes on the lead I'll put the LFO set to filter cutoff so it sounds warped.
for a sub bass u don't really need any advanced synths imo, as sub is inherently a simple sound, like some of the guys said if ur using FL 3xosc should do fine, Reason Subtractor and Malstrom will do the job (i use Malstrom for my subs in Reason)