ive used reaper for a while now, used to use it on linux aswell, it worked alot better on it but linux has a complete lack of compatible softsynths, could only get some vsts to work so came back to windows.
but now the uses for reaper with reason 4 and any of the Native Instruments softs is nothing short of amazing. in like the idea that u everything is within reason to create a tune, but add vsti's and some of the reaper afterfx, they really make bits shine.
ATM I'm creating dubstep tunes, recordings wav loops on battery and recyclin em into reason4 with extra redrum patterns, and rewiring it into reaper.
for all the synths and subs I'm patching a diff instance of massive (reaper allows you to open the same vsti as many times as u like with different patches open, other DAWs ive used only allow 4 or 5 instances of a vsti).
also i like th fact that you can just drop an audio wav into any channel and it drops it into the time line with no need to recycle / timesterch the audio.
I agree with Kama that the midi sequence editor, but then again i dont think you'd be using a daw and vsti's unless you use external midi keyboards and controllers with em? so getting around the editor problem is back to basics - re-record the midi.
one of the most versatile programs Ive used. I'm willing to admit there are plenty of programs that are capable of doin the same little things that make people fall in love with a particular program for them to use, and use well, but Reaper is by far the most advanced DAW / vst host that will rape you wallet, and your mind trying to figure it out.
Kudos to Cocko's for a brilliant product!