It's all jokes of course but one of the points he has is really interesting - he seems to think that if you randomly come up with a good sound its cheating or it isn't worth shit, and that if you use presets you can't really produce.
Which is bollocks IMO. I used to be really anti-preset type of guy when it came to creating sounds, but eventually I understood that actually making music instead of tweaking synth parameters for hours is much more productive and fun. I know how to conjure up a decent pad, a mean bass stab or a neuro reece. But knowing that, I'm even happier using samples or presets, because when I hear a sound I usually get e general idea on how it's been made and I get an idea on how to use it in a creative way rather than how to tweak is so nobody recognizes it as a preset. The girls on the dancefloor couldn't care less whether the reece was a preset or if you spent 3 hours creating the tonal balance and modulations between a lowpassed square and a 25% pulse wave. Sound design is a useful skill, but when it comes to making music, it only has use if you can't find a preset that suits your needs. If you pay 250€ for a piece of software, you're perfectly entitled to use the sounds it can offer you.
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And let's admit it: It's all about the girls on the dancefloor.