In my opinion it's best to keep the sub (150hz below)clean and mono...then build your sound up with more distorted bass tracks(depending on the type of tune).
Track1 -sub(150hz below+mono)
Track2 -either copy track 1 and add distortion & stereo widening etc + low cut everything under 150hz
or use a different bass audio sample/synth patch the same note as the sub and add distortion & stereo widening+ low cut everything under 150hz
then on Track3 do the same as Track2 but add a different type of distortion plugin and add even more stereo widening with a low cut even higher....say 1000hz...try different variations of lfo too...
hope this helps a bit...this is the method i usually use.
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Here's an example of some of my tunes using this method...give or take a few bits n bobs...