I'm not an expert at all at those reeces, but my guess with vsts it is a pretty standard, heavily detuned reece, with loads of distortion, and EQing, compressing. I usually kill alot of the mid frequencies and resonate lowpass filter taking the his. I don't think/hope it would be thread-hijacking since it's on-topic, so; would be really curious to know how you other guys usually EQ these?
For distortion, btw, try out "analtortion". I use it for a lot of stuff that needs to sound downright nasty, especially synths and voices. You need to get a little used to the modulation of this distortion, and the filter included (I usually remove the "Xtra" and "PCH" thingy, though it is sometimes useful), but it has become a staple for me.