there are no hard and fast rules... best thing i can suggest is experimenting using a combination of differnt wave shapes... like a sine, a saw and a square or two square and a saw with the squares at different rates of oscillation...
lfo is also key, even if you are not using it to wobbel, you can use it make an note more organic/human...
then distortion, satuaration, eq bit crushing and many other effects chains will come into play...
you then normally need to bosch a sub bass under to rumble them speakers!
not the answer you want but tough!
ps, listen yo my myspace songs and you can see what i created (synth wise) on abletons operator alone! (no plugins!
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