From personal experience, if you are just starting out, I think Fruity Loops is the most user friendly. However, that being said, I also think fruity loops is the least proffesional sounding (thats not saying you cannot produce a proffesional sound out of it! But you have to know what you are doing in terms of mastering the sounds!).
Steinberg's Cubase or Nuendo sound amazing, but if you are just starting out, these can be very daunting and difficult to master!
There are so many different types of production software out there that you will not be able to get a definate answer from any of us here. Most will simply tell you what they think is best, and what they use.
Your best bet would be to download the demo's of each, play around with them, and see which one you feel most comfortable with.
Good luck, and welcome to the world of music creation!