use several saw waves, one low end, one high end & the other in the middle. make sure they are not harmonic in any way and all 3 notes clash with each other. now distort it to fuck!! so if using reason then add a skream distortion unit and crank the gain up all the way on the warp setting. then using parameter automation, set the volume to fade in at the begining of the bar, and fade out at the end of the bar.
Anyways that would be how id do it, not using reason tho, but it depends on what system ur using.